An evaluation system for electronic retrospective analyses in radiation oncology - Implemented exemplarily for pancreatic cancer
Kessel KA, Jaeger A, Bohn C, Habermehl D, Zhang L, Engelmann U, Bougatf N, Bendl R, Debus J, Combs SE (2013)
Publication Type: Conference contribution
Publication year: 2013
Journal
Book Volume: 8674
Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Event location: USA
ISBN: 9780819494481
DOI: 10.1117/12.2006809
Abstract
To date, conducting retrospective clinical analyses is rather difficult and time consuming. Especially in radiation oncology, handling voluminous datasets from various information systems and different documentation styles efficiently is crucial for patient care and research. With the example of patients with pancreatic cancer treated with radio-chemotherapy, we performed a therapy evaluation by using analysis tools connected with a documentation system. A total number of 783 patients have been documented into a professional, web-based documentation system. Information about radiation therapy, diagnostic images and dose distributions have been imported. For patients with disease progression after neoadjuvant chemoradiation, we designed and established an analysis workflow. After automatic registration of the radiation plans with the follow-up images, the recurrence volumes are segmented manually. Based on these volumes the DVH (dose-volume histogram) statistic is calculated, followed by the determination of the dose applied to the region of recurrence. All results are stored in the database and included in statistical calculations. The main goal of using an automatic evaluation system is to reduce time and effort conducting clinical analyses, especially with large patient groups. We showed a first approach and use of some existing tools, however manual interaction is still necessary. Further steps need to be taken to enhance automation. Already, it has become apparent that the benefits of digital data management and analysis lie in the central storage of data and reusability of the results. Therefore, we intend to adapt the evaluation system to other types of tumors in radiation oncology. © 2013 SPIE.
Involved external institutions
Germany (DE)How to cite
APA:
Kessel, K.A., Jaeger, A., Bohn, C., Habermehl, D., Zhang, L., Engelmann, U.,... Combs, S.E. (2013). An evaluation system for electronic retrospective analyses in radiation oncology - Implemented exemplarily for pancreatic cancer. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. USA.
MLA:
Kessel, Kerstin A., et al. "An evaluation system for electronic retrospective analyses in radiation oncology - Implemented exemplarily for pancreatic cancer." Proceedings of the Medical Imaging 2013: Advanced PACS-Based Imaging Informatics and Therapeutic Applications, USA 2013.
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