Quaranta M, Knapp B, Garzorz N, Mattii M, Pullabhatla V, Pennino D, Andres C, Traidl-Hoffmann C, Cavani A, Theis FJ, Ring J, Schmidt-Weber CB, Eyerich S, Eyerich K (2014)
Publication Type: Journal article
Publication year: 2014
Book Volume: 6
Article Number: 244ra90
Journal Issue: 244
DOI: 10.1126/scitranslmed.3008946
Previous attempts to gain insight into the pathogenesis of psoriasis and eczema by comparing their molecular signatures were hampered by the high interindividual variability of those complex diseases. In patients affected by both psoriasis and nonatopic or atopic eczema simultaneously (n = 24), an intraindividual comparison of the molecular signatures of psoriasis and eczema identified genes and signaling pathways regulated in common and exclusive for each disease across all patients. Psoriasis-specific genes were important regulators of glucose and lipid metabolism, epidermal differentiation, as well as immune mediators of T helper 17 (T
APA:
Quaranta, M., Knapp, B., Garzorz, N., Mattii, M., Pullabhatla, V., Pennino, D.,... Eyerich, K. (2014). Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema. Science Translational Medicine, 6(244). https://doi.org/10.1126/scitranslmed.3008946
MLA:
Quaranta, Maria, et al. "Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema." Science Translational Medicine 6.244 (2014).
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