Emerging Research on Bone Health Using High-Resolution CT and MRI

Liebl H, Baum T, Karampinos DC, Patsch J, Malecki A, Schaff F, Eggl E, Rummeny EJ, Pfeiffer F, Bauer JS (2014)

Publication Type: Journal article, Review article

Publication year: 2014

Journal

Current Radiology Reports Springer

Book Volume: 2

Article Number: 31

Journal Issue: 1

DOI: 10.1007/s40134-013-0031-y

Abstract

Today’s most prevalent bone disease in the western hemisphere is osteoporosis. Predominantly postmenopausal women and older men suffer from bone loss caused by an imbalance in the physiological tissue renewal process between bone formation and resorption. As a result, osteoporosis is associated with fragility fractures, disability, impaired bone regeneration and increased mortality. The World Health Organization based the gold standard for diagnosing osteoporosis on bone mineral density (BMD) measurements using dual X-ray absorptiometry. However, BMD measurements are limited in discriminating subjects with and without osteoporotic fractures and have been shown to only partly reflect successful treatment of osteoporotic fractures. Bone microstructure is an integral determinant of bone strength. Today, new high-resolution imaging techniques such as high-resolution peripheral quantitative computed tomography and high-resolution magnetic resonance imaging make it possible to measure three-dimensional bone microarchitecture and volumetric bone mineral density with high accuracy and a relatively low radiation dose.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Medizinische Universität Wien AT Austria (AT) Klinikum rechts der Isar DE Germany (DE)

How to cite

APA:

Liebl, H., Baum, T., Karampinos, D.C., Patsch, J., Malecki, A., Schaff, F.,... Bauer, J.S. (2014). Emerging Research on Bone Health Using High-Resolution CT and MRI. Current Radiology Reports, 2(1). https://dx.doi.org/10.1007/s40134-013-0031-y

MLA:

Liebl, Hans, et al. "Emerging Research on Bone Health Using High-Resolution CT and MRI." Current Radiology Reports 2.1 (2014).

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