Multiscale multispectral optoacoustic tomography by a stationary wavelet transform prior to unmixing

Taruttis A, Rosenthal A, Kacprowicz M, Burton NC, Ntziachristos V (2014)

Publication Type: Journal article

Publication year: 2014

Journal

IEEE Transactions on Medical Imaging Institute of Electrical and Electronics Engineers (IEEE)

Book Volume: 33

Pages Range: 1194-1202

Article Number: 6748955

Journal Issue: 5

DOI: 10.1109/TMI.2014.2308578

Abstract

Multispectral optoacoustic tomography (MSOT) utilizes broadband ultrasound detection for imaging biologically-relevant optical absorption features at a range of scales. Due to the multiscale and multispectral features of the technology, MSOT comes with distinct requirements in implementation and data analysis. In this work, we investigate the interplay between scale, which depends on ultrasonic detection frequency, and optical multispectral spectral analysis, two dimensions that are unique to MSOT and represent a previously unexplored challenge. We show that ultrasound frequency-dependent artifacts suppress multispectral features and complicate spectral analysis. In response, we employ a wavelet decomposition to perform spectral unmixing on a per-scale basis (or per ultrasound frequency band) and showcase imaging of fine-scale features otherwise hidden by low frequency components. We explain the proposed algorithm by means of simple simulations and demonstrate improved performance in imaging data of blood vessels in human subjects. © 2014 IEEE.

Involved external institutions

University of Groningen / Rijksuniversiteit Groningen NL Netherlands (NL) Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU) / Helmholtz Munich DE Germany (DE)

How to cite

APA:

Taruttis, A., Rosenthal, A., Kacprowicz, M., Burton, N.C., & Ntziachristos, V. (2014). Multiscale multispectral optoacoustic tomography by a stationary wavelet transform prior to unmixing. IEEE Transactions on Medical Imaging, 33(5), 1194-1202. https://dx.doi.org/10.1109/TMI.2014.2308578

MLA:

Taruttis, Adrian, et al. "Multiscale multispectral optoacoustic tomography by a stationary wavelet transform prior to unmixing." IEEE Transactions on Medical Imaging 33.5 (2014): 1194-1202.

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