Suchy C, Massen L, Rognmo O, Van Craenenbroeck EM, Beckers P, Kraigher-Krainer E, Linke A, Adams V, Wisloff U, Pieske B, Halle M (2014)
Publication Type: Journal article
Publication year: 2014
Book Volume: 21
Pages Range: 18-25
Heart failure with preserved left ventricular ejection fraction (HFpEF) currently affects more than seven million Europeans and is the only cardiovascular disease increasing in prevalence and incidence. No pharmacological agent has yet been shown to improve symptoms or prognosis. The most promising way to improve pathophysiology and deprived exercise-tolerance in HFpEF patients seems to be exercise training, but the optimal approach and dose of exercise is still unknown. The major objective of the optimising exercise training in prevention and treatment of diastolic heart failure study (OptimEx-CLIN) is to define the optimal dose of exercise training in patients with HFpEF. In order to optimise adherence, supervision and economic aspects of exercise training a novel telemedical approach will be introduced and investigated. In a prospective randomised multi-centre study, 180 patients with stable symptomatic HFpEF will be randomised (1:1:1) to moderate intensity continuous training, high intensity interval training, or a control group. The training intervention includes three months supervised followed by nine months of telemedically monitored home-based training. The primary endpoint is change in exercise capacity, defined as change in peak oxygen uptake (VO
APA:
Suchy, C., Massen, L., Rognmo, O., Van Craenenbroeck, E.M., Beckers, P., Kraigher-Krainer, E.,... Halle, M. (2014). Optimising exercise training in prevention and treatment of diastolic heart failure (OptimEx-CLIN): Rationale and design of a prospective, randomised, controlled trial. European Journal of Preventive Cardiology, 21, 18-25. https://doi.org/10.1177/2047487314552764
MLA:
Suchy, Christiane, et al. "Optimising exercise training in prevention and treatment of diastolic heart failure (OptimEx-CLIN): Rationale and design of a prospective, randomised, controlled trial." European Journal of Preventive Cardiology 21 (2014): 18-25.
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