X-ray phase-contrast tomography with a compact laser-driven synchrotron source

Eggl E, Schleede S, Bech M, Achterhold K, Loewen R, Ruth RD, Pfeiffer F (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Proceedings of the National Academy of Sciences of the United States of America National Academy of Sciences

Book Volume: 112

Pages Range: 5567-5572

Journal Issue: 18

DOI: 10.1073/pnas.1500938112

Abstract

Between X-ray tubes and large-scale synchrotron sources, a large gap in performance exists with respect to the monochromaticity and brilliance of the X-ray beam. However, due to their size and cost, large-scale synchrotrons are not available for more routine applications in small and medium-sized academic or industrial laboratories. This gap could be closed by laser-driven compact synchrotron light sources (CLS), which use an infrared (IR) laser cavity in combination with a small electron storage ring. Hard X-rays are produced through the process of inverse Compton scattering upon the intersection of the electron bunch with the focused laser beam. The produced X-ray beam is intrinsically monochromatic and highly collimated. This makes a CLS well-suited for applications of more advanced - and more challenging - X-ray imaging approaches, such as X-ray multimodal tomography. Here we present, to our knowledge, the first results of a first successful demonstration experiment in which a monochromatic X-ray beam from a CLS was used for multimodal, i.e., phase-, dark-field, and attenuation-contrast, X-ray tomography. We show results from a fluid phantom with different liquids and a biomedical application example in the form of a multimodal CT scan of a small animal (mouse, ex vivo). The results highlight particularly that quantitative multimodal CT has become feasible with laser-driven CLS, and that the results outperform more conventional approaches.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Lyncean Technologies, Inc. US United States (USA) (US) Stanford National Accelerator Laboratory (SLAC) US United States (USA) (US)

How to cite

APA:

Eggl, E., Schleede, S., Bech, M., Achterhold, K., Loewen, R., Ruth, R.D., & Pfeiffer, F. (2015). X-ray phase-contrast tomography with a compact laser-driven synchrotron source. Proceedings of the National Academy of Sciences of the United States of America, 112(18), 5567-5572. https://doi.org/10.1073/pnas.1500938112

MLA:

Eggl, Elena, et al. "X-ray phase-contrast tomography with a compact laser-driven synchrotron source." Proceedings of the National Academy of Sciences of the United States of America 112.18 (2015): 5567-5572.

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