Quantitative X-ray phase-contrast microtomography from a compact laser-driven betatron source
Wenz J, Schleede S, Khrennikov K, Bech M, Thibault P, Heigoldt M, Pfeiffer F, Karsch S (2015)
Publication Type: Journal article
Publication year: 2015
Journal
Book Volume: 6
Article Number: 7568
DOI: 10.1038/ncomms8568
Abstract
X-ray phase-contrast imaging has recently led to a revolution in resolving power and tissue contrast in biomedical imaging, microscopy and materials science. The necessary high spatial coherence is currently provided by either large-scale synchrotron facilities with limited beamtime access or by microfocus X-ray tubes with rather limited flux. X-rays radiated by relativistic electrons driven by well-controlled high-power lasers offer a promising route to a proliferation of this powerful imaging technology. A laser-driven plasma wave accelerates and wiggles electrons, giving rise to a brilliant keV X-ray emission. This so-called betatron radiation is emitted in a collimated beam with excellent spatial coherence and remarkable spectral stability. Here we present a phase-contrast microtomogram of a biological sample using betatron X-rays. Comprehensive source characterization enables the reconstruction of absolute electron densities. Our results suggest that laser-based X-ray technology offers the potential for filling the large performance gap between synchrotron- and current X-ray tube-based sources.
Involved external institutions
Germany (DE)How to cite
APA:
Wenz, J., Schleede, S., Khrennikov, K., Bech, M., Thibault, P., Heigoldt, M.,... Karsch, S. (2015). Quantitative X-ray phase-contrast microtomography from a compact laser-driven betatron source. Nature Communications, 6. https://doi.org/10.1038/ncomms8568
MLA:
Wenz, J., et al. "Quantitative X-ray phase-contrast microtomography from a compact laser-driven betatron source." Nature Communications 6 (2015).
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