Phase-contrast Hounsfield units of fixated and non-fixated soft-tissue samples
Willner M, Fior G, Marschner M, Birnbacher L, Schock J, Braun C, Fingerle AA, Noel PB, Rummeny EJ, Pfeiffer F, Herzen J (2015)
Publication Type: Journal article
Publication year: 2015
Journal
Book Volume: 10
Article Number: e0137016
Journal Issue: 8
DOI: 10.1371/journal.pone.0137016
Abstract
X-ray phase-contrast imaging is a novel technology that achieves high soft-tissue contrast. Although its clinical impact is still under investigation, the technique may potentially improve clinical diagnostics. In conventional attenuation-based X-ray computed tomography, radiological diagnostics are quantified by Hounsfield units. Corresponding Hounsfield units for phase-contrast imaging have been recently introduced, enabling a setup-independent comparison and standardized interpretation of imaging results. Thus far, the experimental values of few tissue types have been reported; these values have been determined from fixated tissue samples. This study presents phase-contrast Hounsfield units for various types of non-fixated human soft tissues. A large variety of tissue specimens ranging from adipose, muscle and connective tissues to liver, kidney and pancreas tissues were imaged by a grating interferometer with a rotating-anode X-ray tube and a photon-counting detector. Furthermore, we investigated the effects of formalin fixation on the quantitative phase-contrast imaging results. Copyright:
Involved external institutions
Germany (DE)How to cite
APA:
Willner, M., Fior, G., Marschner, M., Birnbacher, L., Schock, J., Braun, C.,... Herzen, J. (2015). Phase-contrast Hounsfield units of fixated and non-fixated soft-tissue samples. PLoS ONE, 10(8). https://doi.org/10.1371/journal.pone.0137016
MLA:
Willner, Marian, et al. "Phase-contrast Hounsfield units of fixated and non-fixated soft-tissue samples." PLoS ONE 10.8 (2015).
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