Detection models for freehand SPECT reconstruction
Hartl A, Shakir DI, Lasser T, Ziegler SI, Navab N (2015)
Publication Type: Journal article
Publication year: 2015
Journal
Book Volume: 60
Pages Range: 1031-1046
Journal Issue: 3
DOI: 10.1088/0031-9155/60/3/1031
Abstract
Nuclear imaging modalities are commonly used tools in today's diagnostics and therapy planning. However for interventional use they suffer from drawbacks which limit their application. Freehand SPECT was developed to provide 3D functional imaging during interventions. It combines a nuclear detector with an optical tracking system to obtain its position and orientation in space and synchronizes this with the detector readings. This information can be used to compute a 3D tomographic reconstruction of an activity distribution of a nuclear tracer. As there is no fixed geometry, the system matrix has to be computed on the fly. This is done with models of the detection process for completely arbitrary freehand acquisitions. The accuracy of the reconstructions is highly dependent on the used models of the detection process. Different models of the detection process were developed and evaluated in this work, in particular two analytical models as well as lookup tablesgenerated from either real measurements or Monte Carlo simulations. We showed that it is possible to perform acceptable reconstructions with a simple but efficient analytical model. The use of lookup tablesto generate the system matrix in Freehand SPECT is a fast solution with good accuracy.
Involved external institutions
Germany (DE)How to cite
APA:
Hartl, A., Shakir, D.I., Lasser, T., Ziegler, S.I., & Navab, N. (2015). Detection models for freehand SPECT reconstruction. Physics in Medicine and Biology, 60(3), 1031-1046. https://doi.org/10.1088/0031-9155/60/3/1031
MLA:
Hartl, Alexander, et al. "Detection models for freehand SPECT reconstruction." Physics in Medicine and Biology 60.3 (2015): 1031-1046.
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