Simon F, Dittmar JO, Brons S, Orschiedt L, Urbschat S, Weber KJ, Debus J, Combs SE, Rieken S (2015)
Publication Type: Journal article
Publication year: 2015
Book Volume: 191
Pages Range: 347-355
Journal Issue: 4
DOI: 10.1007/s00066-014-0778-y
Purpose: Sublethal doses of photon irradiation (IR) are suspected to increase tumor cell migration and support locoregional recurrence of disease, which has already been shown in other cell lines. This manuscript describes the effect of photon and carbon-ion IR on WHO class I meningioma cell migration and provides an approach to the underlying cellular mechanisms. Materials and methods: Meningioma cells were gained operatively at the university hospital in Homburg/Saar, Germany. For migration, membranes (8-µm pore sizes) were coated with collagen I, with collagen IV, and with fibronectin. Cells were analyzed in migration experiments with or without serum stimulation, with or without photon and carbon IR 24 h prior to experiments, and with or without integrin antibodies. Fluorescence-activated cell sorting (FACS) analyses of the integrins ανβ
APA:
Simon, F., Dittmar, J.-O., Brons, S., Orschiedt, L., Urbschat, S., Weber, K.-J.,... Rieken, S. (2015). Integrin-based meningioma cell migration is promoted by photon but not by carbon-ion irradiation Förderung der integrinbasierten Meningeomzellmigration durch Bestrahlung mit Photonen, nicht jedoch durch Bestrahlung mit Kohlenstoffionen. Strahlentherapie und Onkologie, 191(4), 347-355. https://doi.org/10.1007/s00066-014-0778-y
MLA:
Simon, Florian, et al. "Integrin-based meningioma cell migration is promoted by photon but not by carbon-ion irradiation Förderung der integrinbasierten Meningeomzellmigration durch Bestrahlung mit Photonen, nicht jedoch durch Bestrahlung mit Kohlenstoffionen." Strahlentherapie und Onkologie 191.4 (2015): 347-355.
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