A bi-ventricular cardiac atlas built from 1000+ high resolution MR images of healthy subjects and an analysis of shape and motion

Bai W, Shi W, De Marvao A, Dawes TJW, O'Regan DP, Cook SA, Rueckert D (2015)


Publication Type: Journal article

Publication year: 2015

Journal

Book Volume: 26

Pages Range: 133-145

Journal Issue: 1

DOI: 10.1016/j.media.2015.08.009

Abstract

Atlases encode valuable anatomical and functional information from a population. In this work, a bi-ventricular cardiac atlas was built from a unique data set, which consists of high resolution cardiac MR images of 1000+ normal subjects. Based on the atlas, statistical methods were used to study the variation of cardiac shapes and the distribution of cardiac motion across the spatio-temporal domain. We have shown how statistical parametric mapping (SPM) can be combined with a general linear model to study the impact of gender and age on regional myocardial wall thickness. Finally, we have also investigated the influence of the population size on atlas construction and atlas-based analysis. The high resolution atlas, the statistical models and the SPM method will benefit more studies on cardiac anatomy and function analysis in the future.

Involved external institutions

How to cite

APA:

Bai, W., Shi, W., De Marvao, A., Dawes, T.J.W., O'Regan, D.P., Cook, S.A., & Rueckert, D. (2015). A bi-ventricular cardiac atlas built from 1000+ high resolution MR images of healthy subjects and an analysis of shape and motion. Medical Image Analysis, 26(1), 133-145. https://doi.org/10.1016/j.media.2015.08.009

MLA:

Bai, Wenjia, et al. "A bi-ventricular cardiac atlas built from 1000+ high resolution MR images of healthy subjects and an analysis of shape and motion." Medical Image Analysis 26.1 (2015): 133-145.

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