X-ray phase-contrast tomosynthesis of a human ex vivo breast slice with an inverse Compton x-ray source

Eggl E, Schleede S, Bech M, Achterhold K, Grandl S, Sztrokay A, Hellerhoff K, Mayr D, Loewen R, Ruth RD, Reiser MF, Pfeiffer F (2016)

Publication Type: Journal article

Publication year: 2016

Journal

EPL - Europhysics Letters Institute of Physics: EPL

Book Volume: 116

Article Number: 68003

Journal Issue: 6

DOI: 10.1209/0295-5075/116/68003

Abstract

While the performance of conventional x-ray tube sources often suffers from the broad polychromatic spectrum, synchrotrons that could provide highly brilliant x-rays are restricted to large research facilities and impose high investment and maintenance costs. Lately, a new type of compact synchrotron sources has been investigated. These compact light sources (CLS) based on inverse Compton scattering provide quasi-monochromatic hard x-rays. The flux and brilliance yielded by a CLS currently lie between x-ray tube sources and third-generation synchrotrons. The relatively large partially coherent x-ray beam is well suited for the investigation of preclinical applications of grating-based phase-contrast and dark-field imaging. Here we present the first grating-based multimodal tomosynthesis images of a human breast slice acquired at a CLS to investigate the possibilities of improved breast cancer diagnostics.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Lund University / Lunds universitet SE Sweden (SE) Klinikum der Universität München (Großhadern und Innenstadt) DE Germany (DE) Ludwig-Maximilians-Universität (LMU) DE Germany (DE) Lyncean Technologies, Inc. US United States (USA) (US) Stanford National Accelerator Laboratory (SLAC) US United States (USA) (US)

How to cite

APA:

Eggl, E., Schleede, S., Bech, M., Achterhold, K., Grandl, S., Sztrokay, A.,... Pfeiffer, F. (2016). X-ray phase-contrast tomosynthesis of a human ex vivo breast slice with an inverse Compton x-ray source. EPL - Europhysics Letters, 116(6). https://doi.org/10.1209/0295-5075/116/68003

MLA:

Eggl, E., et al. "X-ray phase-contrast tomosynthesis of a human ex vivo breast slice with an inverse Compton x-ray source." EPL - Europhysics Letters 116.6 (2016).

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