Preclinical x-ray dark-field imaging: Foreign body detection
Braig EM, Muenzel D, Fingerle A, Herzen J, Rummeny E, Pfeiffer F, Noer P (2017)
Publication Type: Conference contribution
Publication year: 2017
Journal
Publisher: SPIE
Book Volume: 10132
Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Event location: Orlando, FL, USA
ISBN: 9781510607095
DOI: 10.1117/12.2254261
Abstract
The purpose of this study was to evaluate the performance of X-ray dark-field imaging for detection of retained foreign bodies in ex-vivo hands and feet. X-ray dark-field imaging, acquired with a three-grating Talbot-Lau interferometer, has proven to provide access to sub-resolution structures due to small-angle scattering. The study was institutional review board (IRB) approved. Foreign body parts included pieces of wood and metal which were placed in a formalin fixated human ex-vivo hand. The samples were imaged with a grating-based interferometer consisting of a standard microfocus X-ray tube (60 kVp, 100 W) and a Varian 2520-DX detector (pixel size: 127 μm). The attenuation and the dark-field signals provide complementary diagnostic information for this clinical task. With regard to detecting of wooden objects, which are clinically the most relevant, only the dark-field image revealed the locations. The signal is especially strong for dry wood which in comparison is poorly to non-visible in computed tomography. The detection of high atomic-number or dense material and wood-like or porous materials in a single X-ray scan is enabled by the simultaneous acquisition of the conventional attenuation and dark-field signal. Our results reveal that with this approach one can reach a significantly improved sensitivity for detection of foreign bodies, while an easy implementation into the clinical arena is becoming feasible.
Involved external institutions
Germany (DE)How to cite
APA:
Braig, E.-M., Muenzel, D., Fingerle, A., Herzen, J., Rummeny, E., Pfeiffer, F., & Noer, P. (2017). Preclinical x-ray dark-field imaging: Foreign body detection. In Taly Gilat Schmidt, Joseph Y. Lo, Thomas G. Flohr (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Orlando, FL, USA: SPIE.
MLA:
Braig, Eva-Maria, et al. "Preclinical x-ray dark-field imaging: Foreign body detection." Proceedings of the Medical Imaging 2017: Physics of Medical Imaging, Orlando, FL, USA Ed. Taly Gilat Schmidt, Joseph Y. Lo, Thomas G. Flohr, SPIE, 2017.
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