NeuBtracker - Imaging neurobehavioral dynamics in freely behaving fish

Symvoulidis P, Lauri A, Stefanoiu A, Cappetta M, Schneider S, Jia H, Stelzl A, Koch M, Perez CC, Myklatun A, Renninger S, Chmyrov A, Lasser T, Wurst W, Ntziachristos V, Westmeyer GG (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Nature Methods Nature Publishing Group

Book Volume: 14

Pages Range: 1079-1082

Journal Issue: 11

DOI: 10.1038/nmeth.4459

Abstract

A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activation during naturalistic behavior.

Involved external institutions

Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU) / Helmholtz Munich DE Germany (DE) Technische Universität München (TUM) DE Germany (DE) Champalimaud Foundation / Fundação Champalimaud PT Portugal (PT)

How to cite

APA:

Symvoulidis, P., Lauri, A., Stefanoiu, A., Cappetta, M., Schneider, S., Jia, H.,... Westmeyer, G.G. (2017). NeuBtracker - Imaging neurobehavioral dynamics in freely behaving fish. Nature Methods, 14(11), 1079-1082. https://doi.org/10.1038/nmeth.4459

MLA:

Symvoulidis, Panagiotis, et al. "NeuBtracker - Imaging neurobehavioral dynamics in freely behaving fish." Nature Methods 14.11 (2017): 1079-1082.

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