Molecular Imaging of Abdominal Aortic Aneurysms

Brangsch J, Reimann C, Collettini F, Buchert R, Botnar RM, Makowski MR (2017)


Publication Type: Journal article, Review article

Publication year: 2017

Journal

Book Volume: 23

Pages Range: 150-164

Journal Issue: 2

DOI: 10.1016/j.molmed.2016.12.002

Abstract

Abdominal aortic aneurysms (AAAs) represent a vascular disease with severe complications. AAAs are currently the overall 10th leading cause of death in western countries and their incidence is rising. Although different diagnostic techniques are currently available in clinical practice, including ultrasound (US), magnetic resonance imaging (MRI), and computed tomography (CT), imaging-based prediction of life-threatening complications such as aneurysm-rupture remains challenging. Molecular imaging provides a novel diagnostic approach for in vivo visualization of biological processes and pathological alterations at a cellular and molecular level. Its overall aim is to improve our understanding of disease pathogenesis and to facilitate novel diagnostic pathways. This review outlines recent preclinical and clinical developments in molecular MRI, positron emission tomography (PET), and single-photon emission computed tomography (SPECT) for imaging of AAAs.

Involved external institutions

How to cite

APA:

Brangsch, J., Reimann, C., Collettini, F., Buchert, R., Botnar, R.M., & Makowski, M.R. (2017). Molecular Imaging of Abdominal Aortic Aneurysms. Trends in Molecular Medicine, 23(2), 150-164. https://dx.doi.org/10.1016/j.molmed.2016.12.002

MLA:

Brangsch, Julia, et al. "Molecular Imaging of Abdominal Aortic Aneurysms." Trends in Molecular Medicine 23.2 (2017): 150-164.

BibTeX: Download