GIFTed Demons: Deformable image registration with local structure-preserving regularization using supervoxels for liver applications

Papiez BW, Franklin JM, Heinrich MP, Gleeson FV, Brady M, Schnabel JA (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Journal of Medical Imaging Society of Photo-optical Instrumentation Engineers (SPIE)

Book Volume: 5

Article Number: 024001

Journal Issue: 2

DOI: 10.1117/1.JMI.5.2.024001

Abstract

Deformable image registration, a key component of motion correction in medical imaging, needs to be efficient and provides plausible spatial transformations that reliably approximate biological aspects of complex human organ motion. Standard approaches, such as Demons registration, mostly use Gaussian regularization for organ motion, which, though computationally efficient, rule out their application to intrinsically more complex organ motions, such as sliding interfaces. We propose regularization of motion based on supervoxels, which provides an integrated discontinuity preserving prior for motions, such as sliding. More precisely, we replace Gaussian smoothing by fast, structure-preserving, guided filtering to provide efficient, locally adaptive regularization of the estimated displacement field. We illustrate the approach by applying it to estimate sliding motions at lung and liver interfaces on challenging four-dimensional computed tomography (CT) and dynamic contrast-enhanced magnetic resonance imaging datasets. The results show that guided filter-based regularization improves the accuracy of lung and liver motion correction as compared to Gaussian smoothing. Furthermore, our framework achieves state-of-the-art results on a publicly available CT liver dataset.

Involved external institutions

University of Oxford GB United Kingdom (GB) Universität zu Lübeck DE Germany (DE) Oxford University Hospitals NHS Foundation Trust GB United Kingdom (GB)

How to cite

APA:

Papiez, B.W., Franklin, J.M., Heinrich, M.P., Gleeson, F.V., Brady, M., & Schnabel, J.A. (2018). GIFTed Demons: Deformable image registration with local structure-preserving regularization using supervoxels for liver applications. Journal of Medical Imaging, 5(2). https://doi.org/10.1117/1.JMI.5.2.024001

MLA:

Papiez, Bartlomiej W., et al. "GIFTed Demons: Deformable image registration with local structure-preserving regularization using supervoxels for liver applications." Journal of Medical Imaging 5.2 (2018).

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