Tilted grating phase-contrast computed tomography using statistical iterative reconstruction

Birnbacher L, Viermetz M, Noichl W, Allner S, Fehringer A, Marschner M, Von Teuffenbach M, Willner M, Achterhold K, Noel PB, Koehler T, Herzen J, Pfeiffer F (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Scientific Reports Nature Publishing Group: Open Access Journals - Option B

Book Volume: 8

Article Number: 6608

Journal Issue: 1

DOI: 10.1038/s41598-018-25075-7

Abstract

Grating-based phase-contrast computed tomography (GBPC-CT) enables increased soft tissue differentiation, but often suffers from streak artifacts when performing high-sensitivity GBPC-CT of biomedical samples. Current GBPC-CT setups consist of one-dimensional gratings and hence allow to measure only the differential phase-contrast (DPC) signal perpendicular to the direction of the grating lines. Having access to the full two-dimensional DPC signal can strongly reduce streak artefacts showing up as characteristic horizontal lines in the reconstructed images. GBPC-CT with gratings tilted by 45° around the optical axis, combining opposed projections, and reconstructing with filtered backprojection is one method to retrieve the full three-dimensional DPC signal. This approach improves the quality of the tomographic data as already demonstrated at a synchrotron facility. However, additional processing and interpolation is necessary, and the approach fails when dealing with cone-beam geometry setups. In this work, we employ the tilted grating configuration with a laboratory GBPC-CT setup with cone-beam geometry and use statistical iterative reconstruction (SIR) with a forward model accounting for diagonal grating alignment. Our results show a strong reduction of streak artefacts and significant increase in image quality. In contrast to the prior approach our proposed method can be used in a laboratory environment due to its cone-beam compatibility.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Philips Deutschland GmbH DE Germany (DE)

How to cite

APA:

Birnbacher, L., Viermetz, M., Noichl, W., Allner, S., Fehringer, A., Marschner, M.,... Pfeiffer, F. (2018). Tilted grating phase-contrast computed tomography using statistical iterative reconstruction. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-25075-7

MLA:

Birnbacher, Lorenz, et al. "Tilted grating phase-contrast computed tomography using statistical iterative reconstruction." Scientific Reports 8.1 (2018).

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