Blood vessel imaging using radiofrequency-induced second harmonic acoustic response

Huang Y, Kellnberger S, Sergiadis G, Ntziachristos V (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Scientific Reports Nature Publishing Group: Open Access Journals - Option B

Book Volume: 8

Article Number: 15522

Journal Issue: 1

DOI: 10.1038/s41598-018-33732-0

Abstract

We introduce a contrast mechanism for visualizing blood vessels based on radiofrequency-induced second harmonic acoustic (RISHA) signals sensing blood conductivity. We develop a novel imaging system using commonly available inexpensive components, and demonstrate in vivo RISHA visualization of blood vessels based on low-power quasi-continuous radiofrequency excitation of tissue at frequencies of a few MHz. We show how the novel approach also implicitly enables radiofrequency-induced passive ultrasound imaging and can be readily applied to non-invasive imaging of blood vessels ex vivo and in vivo. We discuss the implications of non-invasive conductivity measurements in the context of biomedical applications.

Involved external institutions

Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU) / Helmholtz Munich DE Germany (DE)

How to cite

APA:

Huang, Y., Kellnberger, S., Sergiadis, G., & Ntziachristos, V. (2018). Blood vessel imaging using radiofrequency-induced second harmonic acoustic response. Scientific Reports, 8(1). https://dx.doi.org/10.1038/s41598-018-33732-0

MLA:

Huang, Yuanhui, et al. "Blood vessel imaging using radiofrequency-induced second harmonic acoustic response." Scientific Reports 8.1 (2018).

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