Colleran R, Kufner S, Mehilli J, Rosenbeiger C, Schuepke S, Hoppmann P, Joner M, Mankerious N, Fusaro M, Cassese S, Abdel-Wahab M, Neumann FJ, Richardt G, Ibrahim T, Schunkert H, Laugwitz KL, Kastrati A, Byrne RA (2018)
Publication Type: Journal article
Publication year: 2018
Book Volume: 71
Pages Range: 1973-1982
Journal Issue: 18
DOI: 10.1016/j.jacc.2018.03.456
Background: In the ISAR-CABG (Is Drug-Eluting-Stenting Associated with Improved Results in Coronary Artery Bypass Grafts?) trial, clinical outcomes at 1 year in patients undergoing treatment of saphenous vein graft lesions were superior with drug-eluting stents (DES) versus bare-metal stents. Objectives: The authors compared outcomes between treatment groups at 5 years. Methods: Patients were randomized (1:1:1:3) to receive DES (either permanent-polymer paclitaxel-eluting stents, permanent-polymer sirolimus-eluting stents, or biodegradable-polymer sirolimus-eluting stents) or bare-metal stents. The primary endpoint was the combined incidence of death, myocardial infarction (MI), or target lesion revascularization (TLR). Secondary endpoints were the composite of death or MI and TLR. Results: A total of 610 patients were allocated to treatment with DES (n = 303) or bare-metal stents (n = 307). At 5 years, the primary endpoint occurred in 159 (55.5%) versus 157 (53.6%) patients in the DES and bare-metal stent groups, respectively (hazard ratio [HR]: 0.98; 95% confidence interval [CI]: 0.79 to 1.23; p = 0.89). There was interaction between treatment effect and time (p
APA:
Colleran, R., Kufner, S., Mehilli, J., Rosenbeiger, C., Schuepke, S., Hoppmann, P.,... Byrne, R.A. (2018). Efficacy Over Time With Drug-Eluting Stents in Saphenous Vein Graft Lesions. Journal of the American College of Cardiology, 71(18), 1973-1982. https://doi.org/10.1016/j.jacc.2018.03.456
MLA:
Colleran, Roisin, et al. "Efficacy Over Time With Drug-Eluting Stents in Saphenous Vein Graft Lesions." Journal of the American College of Cardiology 71.18 (2018): 1973-1982.
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