Tβ4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs

Ziegler T, Baehr A, Howe A, Klett K, Husada W, Weber C, Laugwitz KL, Kupatt C, Hinkel R (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Molecular Therapy Cell Press

Book Volume: 26

Pages Range: 1706-1714

Journal Issue: 7

DOI: 10.1016/j.ymthe.2018.06.004

Abstract

Cardiovascular risk factors, such as hypercholesterolemia, impair cardiac function in chronic ischemia. Ziegler et al. demonstrate that cardiac transduction of thymosin β4 is capable of inducing therapeutic neovascularization and, thereby, improving cardiac function in a translational large animal model with cardiovascular risk factor.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Ludwig-Maximilians-Universität (LMU) DE Germany (DE)

How to cite

APA:

Ziegler, T., Baehr, A., Howe, A., Klett, K., Husada, W., Weber, C.,... Hinkel, R. (2018). Tβ4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs. Molecular Therapy, 26(7), 1706-1714. https://doi.org/10.1016/j.ymthe.2018.06.004

MLA:

Ziegler, Tilman, et al. "Tβ4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs." Molecular Therapy 26.7 (2018): 1706-1714.

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