Bobenko A, Bartels I, Muench M, Trippel T, Lindhorst R, Nolte K, Herrmann-Lingen C, Halle M, Duvinage A, Duengen HD, Gelbrich G, Tschoepe C, Hasenfuss G, Wachter R, Pieske B, Edelmann F (2018)
Publication Type: Journal article
Publication year: 2018
Book Volume: 5
Pages Range: 53-62
Journal Issue: 1
DOI: 10.1002/ehf2.12227
Aims: Heart failure with preserved ejection fraction (HFpEF) remains a common condition with no pharmacological treatment. Physical activity (PA) improves symptoms and quality of life (QoL), but no clear recommendations exist on PA in HFpEF patients. We investigated the association of PA (amount/intensity) on clinical phenotype in HFpEF. Methods and results: The Aldosterone in Diastolic Heart Failure trial investigated spironolactone vs. placebo in stable HFpEF patients. At baseline, all patients underwent detailed phenotypization including echocardiography, cardiopulmonary exercise testing, 6 minute walking test (6MWT), and QoL assessment (36-item Short-Form questionnaire). PA was assessed by a self-report questionnaire, classified in metabolic equivalents of task (MET) and analysed with regard to exercise capacity, diastolic function, and QoL. Four hundred twenty-two patients (52% women, age 67 ± 8 years, New York Heart Association II and III) were classified by weekly MET hours into a low (<70), middle (70–140), or high (>140) level of PA. Total PA correlated positively with 6MWT distance (r = 0.17; P = 0.002) and physical function of QoL (r = 0.10; P = 0.05), but not with peak oxygen uptake (peakVO
APA:
Bobenko, A., Bartels, I., Muench, M., Trippel, T., Lindhorst, R., Nolte, K.,... Edelmann, F. (2018). Amount or intensity? Potential targets of exercise interventions in patients with heart failure with preserved ejection fraction. ESC Heart Failure, 5(1), 53-62. https://doi.org/10.1002/ehf2.12227
MLA:
Bobenko, Anna, et al. "Amount or intensity? Potential targets of exercise interventions in patients with heart failure with preserved ejection fraction." ESC Heart Failure 5.1 (2018): 53-62.
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