The Role of Particle Therapy for the Treatment of Skull Base Tumors and Tumors of the Central Nervous System (CNS)

Diehl CD, Halasz LM, Wilkens JJ, Grosu AL, Combs SE (2019)

Publication Type: Journal article, Review article

Publication year: 2019

Journal

Topics in Magnetic Resonance Imaging Lippincott, Williams & Wilkins

Book Volume: 28

Pages Range: 49-61

Journal Issue: 2

DOI: 10.1097/RMR.0000000000000197

Abstract

Radiation therapy (RT) is a mainstay in the interdisciplinary treatment of brain tumors of the skull base and brain. Technical innovations during the past 2 decades have allowed for increasingly precise treatment with better sparing of adjacent healthy tissues to prevent treatment-related side effects that influence patients' quality of life. Particle therapy with protons and charged ions offer favorable kinetics with sharp dose deposition in a well-defined depth (Bragg-Peak) and a steep radiation fall-off beyond that maximum. This review highlights the role of particle therapy in the management of primary brain tumors and tumors of the skull base.

Involved external institutions

Klinikum rechts der Isar DE Germany (DE) University of Washington US United States (USA) (US) Universitätsklinikum Freiburg DE Germany (DE)

How to cite

APA:

Diehl, C.D., Halasz, L.M., Wilkens, J.J., Grosu, A.-L., & Combs, S.E. (2019). The Role of Particle Therapy for the Treatment of Skull Base Tumors and Tumors of the Central Nervous System (CNS). Topics in Magnetic Resonance Imaging, 28(2), 49-61. https://doi.org/10.1097/RMR.0000000000000197

MLA:

Diehl, Christian D., et al. "The Role of Particle Therapy for the Treatment of Skull Base Tumors and Tumors of the Central Nervous System (CNS)." Topics in Magnetic Resonance Imaging 28.2 (2019): 49-61.

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