Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT and MRI in a multicenter setting
Lerchbaumer MH, Putz FJ, Ruebenthaler J, Rogasch J, Jung EM, Clevert DA, Hamm B, Makowski M, Fischer T (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 75
Pages Range: 419-429
Journal Issue: 4
DOI: 10.3233/CH-190764
Abstract
PURPOSE: Contrast-enhanced-ultrasound (CEUS) has been frequently used in assessment of cystic renal lesions. OBJECTIVE: The aim of this study was to investigate the Bosniak classification in CEUS compared to CT and MRI in a multi-center setting. METHODS: Bosniak classification in CEUS examinations of cystic renal lesions were compared to imaging findings in computed-tomography (ceCT) and magnetic-resonance-imaging (ceMRI). Imaging results were correlated to histopathological reports. All examinations were performed by experts (EFSUMB level 3) using up-to-date CEUS examination-protocols. RESULTS: Overall, 173 cystic renal lesions were compared to subgroups CT (n = 87) and MRI (n = 86). Using Bosniak-classification 64/87 renal cysts (73.6%) were rated equal compared to CT with upgrade of four lesions (4.6%) and downgrade of 19 lesions (21.8%) by CT (Intra-class-correlation [ICC] coefficient of 0.824 [p < 0.001]). CEUS compared to MRI, presenting different scoring especially in classes Bosniak IIF (n = 16/31) and Bosniak III (n = 16/28) with an ICC coefficient of 0.651 (p < 0.001). CONCLUSION: CEUS can visualize even finest septal and small nodular wall enhancement, which may result in an upgrade of cystic lesions into a higher Bosniak class compared to CT or MRI. Thus, a modification of the Bosniak classification on CEUS may reduce unnecessary biopsies and surgery.
Involved external institutions
Charité - Universitätsmedizin Berlin
Germany (DE)
Universitätsklinikum Regensburg
Germany (DE)
Ludwig-Maximilians-Universität (LMU)
Germany (DE)
Germany (DE)
Universitätsklinikum Regensburg
Germany (DE)
Ludwig-Maximilians-Universität (LMU)
Germany (DE)
How to cite
APA:
Lerchbaumer, M.H., Putz, F.J., Ruebenthaler, J., Rogasch, J., Jung, E.-M., Clevert, D.-A.,... Fischer, T. (2020). Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT and MRI in a multicenter setting. Clinical Hemorheology and Microcirculation, 75(4), 419-429. https://doi.org/10.3233/CH-190764
MLA:
Lerchbaumer, Markus Herbert, et al. "Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT and MRI in a multicenter setting." Clinical Hemorheology and Microcirculation 75.4 (2020): 419-429.
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