Clostridioides (Clostridium) difficile Pacemaker Infection

Berkefeld A, Berger FK, Gartner BC, Wantia N, Prinzing A, Laugwitz KL, Busch DH, Rothe K (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Open Forum Infectious Diseases Oxford University Press

Book Volume: 7

Article Number: ofaa487

Journal Issue: 12

DOI: 10.1093/ofid/ofaa487

Abstract

Clostridioides difficile is the leading cause of antibiotic-associated nosocomial diarrhea, but extra-intestinal manifestations are rare. We describe the first documented case of bacteraemia with pacemaker pocket and lead infection with the toxigenic C. difficile ribotype 014 with a lack of abdominal symptoms. The patient underwent pacemaker extraction and treatment with intravenous and oral vancomycin. Genotyping and molecular subtyping revealed clonality between pacemaker and intestinal isolates. This case illustrates the risk of intravascular device infections due to C. difficile. Even asymptomatic C. difficile colonization might pose a risk for prosthetic material infection.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Universität des Saarlandes (UdS) DE Germany (DE)

How to cite

APA:

Berkefeld, A., Berger, F.K., Gartner, B.C., Wantia, N., Prinzing, A., Laugwitz, K.-L.,... Rothe, K. (2020). Clostridioides (Clostridium) difficile Pacemaker Infection. Open Forum Infectious Diseases, 7(12). https://doi.org/10.1093/ofid/ofaa487

MLA:

Berkefeld, Anna, et al. "Clostridioides (Clostridium) difficile Pacemaker Infection." Open Forum Infectious Diseases 7.12 (2020).

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