Neuro-oncology management during the COVID-19 pandemic with a focus on WHO grades III and IV gliomas

Bernhardt D, Wick W, Weiss SE, Sahgal A, Lo SS, Suh JH, Chang EL, Foote M, Perry J, Meyer B, Vajkoczy P, Wen PY, Straube C, Pigorsch S, Wilkens JJ, Combs SE (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Neuro-Oncology Oxford University Press

Book Volume: 22

Pages Range: 928-935

Journal Issue: 7

DOI: 10.1093/neuonc/noaa113

Abstract

Background: Because of the increased risk in cancer patients of developing complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), physicians have to balance the competing risks of the negative impact of the pandemic and the primary tumor disease. In this consensus statement, an international group of experts present mitigation strategies and treatment guidance for patients suffering from high grade gliomas (HGGs) during the coronavirus disease 2019 (COVID-19) pandemic. Methods Sixteen: international experts in the treatment of HGG contributed to this consensus-based practice recommendation, including neuro-oncologists, neurosurgeons, radiation oncologists, and a medical physicist. Generally, treatment of neuro-oncological patients cannot be significantly delayed and initiating therapy should not be outweighed by COVID-19. We present detailed interdisciplinary treatment strategies for molecular subgroups in 2 pandemic scenarios, a scale-up phase and a crisis phase. Conclusion: This practice recommendation presents a pragmatic framework and consensus-based mitigation strategies for the treatment of HGG patients during the SARS-CoV-2 pandemic.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Ruprecht-Karls-Universität Heidelberg DE Germany (DE) Fox Chase Cancer Center US United States (USA) (US) University of Toronto CA Canada (CA) University of Washington US United States (USA) (US) Cleveland Clinic US United States (USA) (US) University of Southern California (USC) US United States (USA) (US) University of Queensland AU Australia (AU) Klinikum rechts der Isar DE Germany (DE) Charité - Universitätsmedizin Berlin DE Germany (DE) Dana-Farber Brigham and Women's Cancer Center US United States (USA) (US)

How to cite

APA:

Bernhardt, D., Wick, W., Weiss, S.E., Sahgal, A., Lo, S.S., Suh, J.H.,... Combs, S.E. (2020). Neuro-oncology management during the COVID-19 pandemic with a focus on WHO grades III and IV gliomas. Neuro-Oncology, 22(7), 928-935. https://doi.org/10.1093/neuonc/noaa113

MLA:

Bernhardt, Denise, et al. "Neuro-oncology management during the COVID-19 pandemic with a focus on WHO grades III and IV gliomas." Neuro-Oncology 22.7 (2020): 928-935.

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