Liu N, O'Connor P, Gujrati V, Gorpas D, Glasl S, Blutke A, Walch A, Kleigrewe K, Sattler M, Plettenburg O, Ntziachristos V (2021)
Publication Type: Journal article
Publication year: 2021
Book Volume: 10
Article Number: 2002115
Journal Issue: 9
Near-infrared (NIR) light absorbing theranostic agents can integrate optoacoustic imaging and photothermal therapy for effective personalized precision medicine. However, most of these agents face the challenges of unstable optical properties, material-associated toxicity, and nonbiodegradability, all of which limit their biomedical application. Several croconaine-based organic agents able to overcome some of these limitations have been recently reported, but these suffer from complicated multistep synthesis protocols. Herein, the use of CR760, a croconaine dye with excellent optical properties, is reported for nanoparticle formulation and subsequent optoacoustic imaging and photothermal therapy. Importantly, CR760 can be conveniently prepared in a single step from commercially available materials. Furthermore, CR760 can be covalently attached, via a polyethylene glycol linker, to the α
APA:
Liu, N., O'Connor, P., Gujrati, V., Gorpas, D., Glasl, S., Blutke, A.,... Ntziachristos, V. (2021). Facile Synthesis of a Croconaine-Based Nanoformulation for Optoacoustic Imaging and Photothermal Therapy. Advanced Healthcare Materials, 10(9). https://doi.org/10.1002/adhm.202002115
MLA:
Liu, Nian, et al. "Facile Synthesis of a Croconaine-Based Nanoformulation for Optoacoustic Imaging and Photothermal Therapy." Advanced Healthcare Materials 10.9 (2021).
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