Gevaert AB, Mueller S, Winzer EB, Duvinage A, Van De Heyning CM, Pieske-Kraigher E, Beckers PJ, Edelmann F, Wisloff U, Pieske B, Adams V, Halle M, Van Craenenbroeck EM (2022)
Publication Type: Journal article
Publication year: 2022
Book Volume: 12
Article Number: 757268
DOI: 10.3389/fphys.2021.757268
Aims: Iron deficiency (ID) is linked to reduced aerobic exercise capacity and poor prognosis in patients with heart failure (HF) with reduced ejection fraction (HFrEF); however, data for HF with preserved ejection fraction (HFpEF) is scarce. We assessed the relationship between iron status and diastolic dysfunction as well as aerobic exercise capacity in HFpEF, and the contribution of iron status to patient phenotyping. Methods and Results: Among 180 patients with HFpEF (66% women; median age, 71 years) recruited for the Optimizing Exercise Training in Prevention and Treatment of Diastolic HF (OptimEx-Clin) trial, baseline iron status, including iron, ferritin, and transferrin saturation, was analyzed (n = 169) in addition to exercise capacity (peak oxygen uptake [peak V̇O
APA:
Gevaert, A.B., Mueller, S., Winzer, E.B., Duvinage, A., Van De Heyning, C.M., Pieske-Kraigher, E.,... Van Craenenbroeck, E.M. (2022). Iron Deficiency Impacts Diastolic Function, Aerobic Exercise Capacity, and Patient Phenotyping in Heart Failure With Preserved Ejection Fraction: A Subanalysis of the OptimEx-Clin Study. Frontiers in Physiology, 12. https://doi.org/10.3389/fphys.2021.757268
MLA:
Gevaert, Andreas B., et al. "Iron Deficiency Impacts Diastolic Function, Aerobic Exercise Capacity, and Patient Phenotyping in Heart Failure With Preserved Ejection Fraction: A Subanalysis of the OptimEx-Clin Study." Frontiers in Physiology 12 (2022).
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