Peschel DP, Duesberg M, Peeken JC, Kaiser JC, Borm KJ, Sommer K, Combs SE, Muench S (2022)
Publication Type: Journal article
Publication year: 2022
Book Volume: 12
Article Number: 22333
Journal Issue: 1
DOI: 10.1038/s41598-022-26641-w
The extent of elective nodal irradiation (ENI) in patients undergoing definitive chemoradiotherapy (dCRT) for esophageal squamous cell carcinoma (ESCC) remains unclear. The aim of this dosimetric study was to evaluate the extent of incidental nodal irradiation using modern radiation techniques. A planning target volume (PTV) was generated for 30 patients with node-negative esophageal carcinoma (13 cervical/upper third, 7 middle third, 10 lower third/abdomen). Thereby, no elective nodal irradiation (ENI) was intended. Both three-dimensional conformal radiotherapy (3D-CRT) and volumetric-modulated arc therapy (VMAT) treatment plans (50 Gy in 25 fractions) were calculated for all patients. Fifteen nodal stations were contoured according to the definitions of the AJCC and investigated in regard to dosimetric parameters. Compared to 3D-CRT, VMAT was associated with lower dose distribution to the organs at risk (lower D
APA:
Peschel, D.P., Duesberg, M., Peeken, J.C., Kaiser, J.C., Borm, K.J., Sommer, K.,... Muench, S. (2022). Incidental nodal irradiation in patients with esophageal cancer undergoing (chemo)radiation with 3D-CRT or VMAT. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-26641-w
MLA:
Peschel, David Paul, et al. "Incidental nodal irradiation in patients with esophageal cancer undergoing (chemo)radiation with 3D-CRT or VMAT." Scientific Reports 12.1 (2022).
BibTeX: Download