Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature

Thrull M, Atasi K, Boese LM, Cakar M, Heller U, Jansen N, Menzel LC, Omaimen H, Theis K, Karacic D, Dimov D, Coras R, Klingebiel R (2023)


Publication Type: Journal article, Review article

Publication year: 2023

Journal

Book Volume: 2023

DOI: 10.1155/2023/4727288

Abstract

We report the rare occurrence of a temporal glioblastoma multiforme (GBM) showing transdural tumor extension into adjacent mastoid cells. As the dura mater provides a barrier to intraaxial tumors, GBM seldom penetrates into the skull base, even though it is a high-grade astrocytoma with a tendency to spread. Yet, some mechanisms of GBM-induced skull invasion have been identified, making this entity a very rare but nonetheless relevant differential diagnosis in otherwise ambiguous cases of an intracerebral tumor extending into the skull base. In addition, imaging markers that may assist in distinguishing extra- from intraaxial tumor infiltration of the temporal bone are described.

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How to cite

APA:

Thrull, M., Atasi, K., Boese, L.-M., Cakar, M., Heller, U., Jansen, N.,... Klingebiel, R. (2023). Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature. Case Reports in Otolaryngology, 2023. https://doi.org/10.1155/2023/4727288

MLA:

Thrull, Michael, et al. "Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature." Case Reports in Otolaryngology 2023 (2023).

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