Multiscale modeling of virus replication and spread
Kumberger P, Frey F, Schwarz US, Graw F (2016)
Publication Type: Journal article, Review article
Publication year: 2016
Journal
Pages Range: 1972-1986
Abstract
Replication and spread of human viruses is based on the simultaneous exploitation of many different host functions, bridging multiple scales in space and time. Mathematical modeling is essential to obtain a systems-level understanding of how human viruses manage to proceed through their life cycles. Here, we review corresponding advances for viral systems of large medical relevance, such as human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV). We will outline how the combination of mathematical models and experimental data has advanced our quantitative knowledge about various processes of these pathogens, and how novel quantitative approaches promise to fill remaining gaps.
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Germany (DE)How to cite
APA:
Kumberger, P., Frey, F., Schwarz, U.S., & Graw, F. (2016). Multiscale modeling of virus replication and spread. FEBS letters, 1972-1986. https://doi.org/10.1002/1873-3468.12095
MLA:
Kumberger, Peter, et al. "Multiscale modeling of virus replication and spread." FEBS letters (2016): 1972-1986.
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