Russ M, Steiner E, Boemke W, Busch T, Melzer-Gartzke C, Taher M, Badulak J, Weber-Carstens S, Swenson ER, Francis RCE, Pickerodt PA (2022)
Publication Type: Journal article
Publication year: 2022
Book Volume: 68
Pages Range: 721-729
Journal Issue: 5
DOI: 10.1097/MAT.0000000000001592
The contribution of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) to systemic oxygen delivery is determined by the ratio of total extracorporeal blood flow (Q˙EC) to cardiac output (Q˙). Thermodilution-based measurements of Q˙ may be compromised by blood recirculating through the ECMO (recirculation fraction; Rf). We measured the effects of Q˙EC and Rf on classic thermodilution-based measurements of Q˙ in six anesthetized pigs. An ultrasound flow probe measured total aortic blood flow (Q˙A0) at the aortic root. Rf was quantified with the ultrasound dilution technique. Q˙EC was set to 0-125% of Q˙A0 and Q˙ was measured using a pulmonary artery catheter (PAC) in healthy and lung injured animals. PAC overestimated Q˙ (Q˙Pa) at all Q˙EC settings compared to Q˙A0. The mean bias between both methods was 2.1 L/min in healthy animals and 2.7 L/min after lung injury. The difference between Q˙Pa and Q˙A0 increased with an Q˙EC of 75-125%/Q˙A0 compared to Q
APA:
Russ, M., Steiner, E., Boemke, W., Busch, T., Melzer-Gartzke, C., Taher, M.,... Pickerodt, P.A. (2022). Extracorporeal Membrane Oxygenation Blood Flow and Blood Recirculation Compromise Thermodilution-Based Measurements of Cardiac Output. Asaio Journal, 68(5), 721-729. https://doi.org/10.1097/MAT.0000000000001592
MLA:
Russ, Martin, et al. "Extracorporeal Membrane Oxygenation Blood Flow and Blood Recirculation Compromise Thermodilution-Based Measurements of Cardiac Output." Asaio Journal 68.5 (2022): 721-729.
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