Current strategies against multi-drug resistant organisms Multiresistente Erreger - Infektionsmanagement 2015

Pletz MW, Eckmann C, Hagel S, Huber K, Kaemmerer W, Schmitz FJ, Wilke M, Grabein B, Heppner HJ (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Deutsche Medizinische Wochenschrift Georg Thieme Verlag

Book Volume: 140

Pages Range: 975-981

Journal Issue: 13

DOI: 10.1055/s-0041-102452

Abstract

The global spread of multi-drug resistant organisms (MDRO) is a major threat to public health. Fighting MDRO spread requires a multi-faceted approach as summarized in the German Antibiotic Resistance Strategy (DART). In the hospital, this includes antibiotic stewardship concepts and strict infection control measures. Treatment of MDRO is sophisticated. Within the last years, several antibiotics with activity against MRSA were launched and facilitate an individual therapy according to site of infection and co-morbidities. In contrast, novel antibiotics against carbapenemase producing Gram-negatives are still lacking. Current studies have shown, that a colistin-based combination treatment can improve the prognosis in these patients. The following article reviews MDRO definitions, burden of disease, treatment options and general strategies against MDRO.

Authors with CRIS profile

Hans Jürgen Heppner

Involved external institutions

Universitätsklinikum Augsburg DE Germany (DE) Klinikum Peine DE Germany (DE) Universitätsklinikum Jena DE Germany (DE) Johannes Wesling Klinikum Minden DE Germany (DE) Klinikum der Universität München (Großhadern und Innenstadt) DE Germany (DE) inspiring-health GmbH DE Germany (DE) Universität Witten/Herdecke DE Germany (DE)

How to cite

APA:

Pletz, M.W., Eckmann, C., Hagel, S., Huber, K., Kaemmerer, W., Schmitz, F.-J.,... Heppner, H.J. (2015). Current strategies against multi-drug resistant organisms Multiresistente Erreger - Infektionsmanagement 2015. Deutsche Medizinische Wochenschrift, 140(13), 975-981. https://doi.org/10.1055/s-0041-102452

MLA:

Pletz, Mathias W., et al. "Current strategies against multi-drug resistant organisms Multiresistente Erreger - Infektionsmanagement 2015." Deutsche Medizinische Wochenschrift 140.13 (2015): 975-981.

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