Vaccination in advanced age Impfungen im höheren Lebensalter
Leischker A, Wutzler P, Kwetkat A, Heppner HJ (2018)
Publication Type: Journal article, Review article
Publication year: 2018
Journal
Book Volume: 59
Pages Range: 205-212
Journal Issue: 2
DOI: 10.1007/s00108-017-0358-1
Abstract
Infectious diseases are responsible for up to 5% of fatalities even in developed countries. In addition, there is an increasing susceptibility for infections in elderly people due to physiological aging of the immune system. The principles of vaccination are based on a targeted activation of the human immune system. Principally, a distinction is made between passive immunization, i.e. the application of specific antibodies against a pathogen and active immunization. In active immunization, i.e. vaccination, weakened (attenuated) or dead pathogens or components of pathogens (antigens) are administered. After a latency period that depends on the vaccine, complete immune protection is achieved and immunity is maintained for a certain period of time. In contrast to dead vaccines, by the use of live vaccines there is always a risk for infection with the administered vaccine. In passive immunization antibodies are administered. As a rule passive immunization is carried out in persons who have had contact with an infected person and in whom no or uncertain immunity against the corresponding disease is present. Based on the recommendations of the Standing Committee on Vaccination (STIKO), influenza, pneumococcal, herpes zoster, early summer meningoencephalitis (FSME) and travel vaccines are described.
Authors with CRIS profile
Involved external institutions
Alexianer Krefeld GmbH
Germany (DE)
Universitätsklinikum Jena
Germany (DE)
Universität Witten/Herdecke
Germany (DE)
Germany (DE)
Universitätsklinikum Jena
Germany (DE)
Universität Witten/Herdecke
Germany (DE)
How to cite
APA:
Leischker, A., Wutzler, P., Kwetkat, A., & Heppner, H.J. (2018). Vaccination in advanced age Impfungen im höheren Lebensalter. Internist, 59(2), 205-212. https://doi.org/10.1007/s00108-017-0358-1
MLA:
Leischker, A., et al. "Vaccination in advanced age Impfungen im höheren Lebensalter." Internist 59.2 (2018): 205-212.
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