Lux A, Nimmerjahn F (2011)
Publication Type: Conference contribution
Publication year: 2011
Book Volume: 780
Pages Range: 113-124
Conference Proceedings Title: Advances in Experimental Medicine and Biology
ISBN: 9781441956316
DOI: 10.1007/978-1-4419-5632-3_10
Immunoglobulin G (IgG) molecules are glycoproteins with dual functionality. While participating in the destruction of virally infected cells or healthy tissues during autoimmune disease, IgG antibodies are also used as a therapeutic agent to suppress IgG-triggered autoimmune disease and inflammation. Research of recent years has put the IgG-associated sugar moiety in the spotlight for regulating these opposing activities. This review will focus on how certain IgG glycovariants impact different IgG-dependent effector functions and how this knowledge might be used to further improve the therapeutic effectiveness of this class of molecules. © 2011 Springer Science+Businees Media, LLC.
APA:
Lux, A., & Nimmerjahn, F. (2011). Impact of differential glycosylation on IgG activity. In Bali Pulendran, Peter Katsikis, Stephen Schoenberger (Eds.), Advances in Experimental Medicine and Biology (pp. 113-124).
MLA:
Lux, Anja, and Falk Nimmerjahn. "Impact of differential glycosylation on IgG activity." Proceedings of the Advances in Experimental Medicine and Biology Ed. Bali Pulendran, Peter Katsikis, Stephen Schoenberger, 2011. 113-124.
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