Fiberfox: An extensible system for generating realisticwhite matter software phantoms
Neher PF, Stieltjes B, Maier-Hein KH, Laun FB (2014)
Publication Type: Conference contribution
Publication year: 2014
Publisher: Springer Heidelberg
Pages Range: 105-113
Conference Proceedings Title: Mathematics and Visualization
Event location: JPN
DOI: 10.1007/978-3-319-02475-2_10
Abstract
We present an open-source system, Fiberfox, for generating synthetic diffusion-weighted datasets. Fiberfox enables (1) definition of artificial white matter fibers, (2) signal generation from those fibers using multi-compartment modeling, and (3) simulation of magnetic resonance artifacts including Gibbs ringing, N=2 ghosting and susceptibility distortions. With a comparative hardware phantom study we show that the synthetic datasets closely resemble real acquisitions. To demonstrate the relevance of Fiberfox for current research questions, we reveal the adverse effects of anisotropic voxels on the outcome of 11 different fiber tractography algorithms. Fiberfox is openly available and may find application in the validation and further development of diffusion-weighted image processing techniques such as super-resolution, denoising, tractography, diffusion modeling or artifact correction.
Authors with CRIS profile
Involved external institutions
Germany (DE)How to cite
APA:
Neher, P.F., Stieltjes, B., Maier-Hein, K.H., & Laun, F.B. (2014). Fiberfox: An extensible system for generating realisticwhite matter software phantoms. In Mathematics and Visualization (pp. 105-113). JPN: Springer Heidelberg.
MLA:
Neher, Peter F., et al. "Fiberfox: An extensible system for generating realisticwhite matter software phantoms." Proceedings of the 16th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2013, JPN Springer Heidelberg, 2014. 105-113.
BibTeX: Download