Brief communication: Pitfalls in immunohistochemistry - A recent example

Riechers A, Bosserhoff AK (2012)

Publication Type: Journal article

Publication year: 2012

Journal

International Journal of Clinical and Experimental Pathology e-Century Publishing

Book Volume: 5

Pages Range: 137-139

Journal Issue: 2

Abstract

Immunohistochemistry is an important and valuable technique in many fields of research, although several common pitfalls can lead to wrong or misinterpreted results. A recently published study [1] claims that the protein MIA (melanoma inhibitory activity) is expressed in Purkinje cells in the cerebellum. Careful re-analysis resulted in negative results. Due to these results of our group we feel that this analysis could serve as example for the potential problems in immunohistochemistry caused by the combination of an unspecific antibody and the omission of evaluating control tissue samples.

Authors with CRIS profile

Anja Katrin Boßerhoff

Involved external institutions

Universität Regensburg DE Germany (DE)

How to cite

APA:

Riechers, A., & Bosserhoff, A.K. (2012). Brief communication: Pitfalls in immunohistochemistry - A recent example. International Journal of Clinical and Experimental Pathology, 5(2), 137-139.

MLA:

Riechers, Alexander, and Anja Katrin Bosserhoff. "Brief communication: Pitfalls in immunohistochemistry - A recent example." International Journal of Clinical and Experimental Pathology 5.2 (2012): 137-139.

BibTeX: Download