Batoulis H, Wunsch M, Birkenheier J, Rottlaender A, Gorboulev V, Kuerten S (2015)
Publication Type: Journal article
Publication year: 2015
Book Volume: 158
Pages Range: 47-58
Journal Issue: 1
DOI: 10.1016/j.clim.2015.03.009
In multiple sclerosis (MS) lymphoid follicle-like aggregates have been reported in the meninges of patients. Here we investigated the functional relevance of B cell infiltration into the central nervous system (CNS) in MP4-induced experimental autoimmune encephalomyelitis (EAE), a B cell-dependent mouse model of MS. In chronic EAE, B cell aggregates were characterized by the presence of CXCL13+ and germinal center CD10+ B cells. Germline transcripts were expressed in the CNS and particularly related to T
APA:
Batoulis, H., Wunsch, M., Birkenheier, J., Rottlaender, A., Gorboulev, V., & Kuerten, S. (2015). Central nervous system infiltrates are characterized by features of ongoing B cell-related immune activity in MP4-induced experimental autoimmune encephalomyelitis. Clinical Immunology, 158(1), 47-58. https://doi.org/10.1016/j.clim.2015.03.009
MLA:
Batoulis, Helena, et al. "Central nervous system infiltrates are characterized by features of ongoing B cell-related immune activity in MP4-induced experimental autoimmune encephalomyelitis." Clinical Immunology 158.1 (2015): 47-58.
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