Lilaj L, Fischer T, Guo J, Braun J, Sack I, Hirsch S (2021)
Publication Type: Journal article
Publication year: 2021
Book Volume: 85
Pages Range: 1655-1668
Journal Issue: 3
DOI: 10.1002/mrm.28507
Purpose: Biological soft tissues often have a porous architecture comprising fluid and solid compartments. Upon displacement through physiological or externally induced motion, the relative motion of these compartments depends on poroelastic parameters, such as coupling density ((Formula presented.)) and tissue porosity. This study introduces inversion recovery MR elastography (IR-MRE) (1) to quantify porosity defined as fluid volume over total volume, (2) to separate externally induced shear strain fields of fluid and solid compartments, and (3) to quantify coupling density assuming a biphasic behavior of in vivo brain tissue. Theory and Methods: Porosity was measured in eight tofu phantoms and gray matter (GM) and white matter (WM) of 21 healthy volunteers. Porosity of tofu was compared to values obtained by fluid draining and microscopy. Solid and fluid shear-strain amplitudes and (Formula presented.) were estimated both in phantoms and in in vivo brain. Results: T
APA:
Lilaj, L., Fischer, T., Guo, J., Braun, J., Sack, I., & Hirsch, S. (2021). Separation of fluid and solid shear wave fields and quantification of coupling density by magnetic resonance poroelastography. Magnetic Resonance in Medicine, 85(3), 1655-1668. https://doi.org/10.1002/mrm.28507
MLA:
Lilaj, Ledia, et al. "Separation of fluid and solid shear wave fields and quantification of coupling density by magnetic resonance poroelastography." Magnetic Resonance in Medicine 85.3 (2021): 1655-1668.
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