InVivo time harmonic elastography of the human heart

Tzschaetzsch H, Elgeti T, Rettig K, Kargel C, Klaua R, Schultz M, Braun J, Sack I (2012)

Publication Type: Journal article

Publication year: 2012

Journal

Ultrasound in Medicine and Biology Elsevier

Book Volume: 38

Pages Range: 214-222

Journal Issue: 2

DOI: 10.1016/j.ultrasmedbio.2011.11.002

Abstract

Time harmonic elastography is introduced as a modality for assessing myocardial elasticity changes during the cardiac cycle. It is based on external stimulation and real-time analysis of 30-Hz harmonic shear waves in axial direction of a parasternal line of sight through the lateral heart wall. In 20 healthy volunteers, the externally induced waves showed smaller amplitudes during systole (76.0 ± 30.8 μm) and higher amplitudes during diastole (126.7 ± 52.1 μm). This periodic wave amplitude alteration preceded ventricular contraction and dilation by about 100 ms. The amplitude ratio of 1.75 ± 0.49 indicates a relative change in myocardial shear elasticity on the order of 14 ± 11. These results well agree with observations made by cardiac magnetic resonance elastography for a similar displacement component and region of the heart. The proposed method provides reproducible elastodynamic information on the heart in real-time and may help in diagnosing myocardial relaxation abnormalities in the future. © 2012 World Federation for Ultrasound in Medicine & Biology.

Involved external institutions

Charité - Universitätsmedizin Berlin DE Germany (DE) Universität der Bundeswehr München DE Germany (DE) GAMPT mbH DE Germany (DE)

How to cite

APA:

Tzschaetzsch, H., Elgeti, T., Rettig, K., Kargel, C., Klaua, R., Schultz, M.,... Sack, I. (2012). InVivo time harmonic elastography of the human heart. Ultrasound in Medicine and Biology, 38(2), 214-222. https://doi.org/10.1016/j.ultrasmedbio.2011.11.002

MLA:

Tzschaetzsch, Heiko, et al. "InVivo time harmonic elastography of the human heart." Ultrasound in Medicine and Biology 38.2 (2012): 214-222.

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