Shinde SS, Maschauer S, Prante O (2021)
Publication Type: Journal article, Review article
Publication year: 2021
Book Volume: 14
Journal Issue: 11
DOI: 10.3390/ph14111175
In the field of F-18-chemistry for the development of radiopharmaceuticals for positron emission tomography (PET), various labeling strategies by the use of prosthetic groups have been implemented, including chemoselective F-18-labeling of biomolecules. Among those, chemoselective F-18-fluoroglycosylation methods focus on the sweetening of pharmaceutical radiochemistry by offering a highly valuable tool for the synthesis of F-18-glycoconjugates with suitable in vivo properties for PET imaging studies. A previous review covered the various F-18-fluoroglycosylation methods that were developed and applied as of 2014 (Maschauer and Prante, BioMed. Res. Int. 2014, 214748). This paper is an updated review, providing the recent progress in F-18-fluoroglycosylation reactions and the preclinical application of F-18-glycoconjugates, including small molecules, peptides, and high-molecular-weight proteins.
APA:
Shinde, S.S., Maschauer, S., & Prante, O. (2021). Sweetening Pharmaceutical Radiochemistry by F-18-Fluoroglycosylation: Recent Progress and Future Prospects. Pharmaceuticals, 14(11). https://doi.org/10.3390/ph14111175
MLA:
Shinde, Sandip S., Simone Maschauer, and Olaf Prante. "Sweetening Pharmaceutical Radiochemistry by F-18-Fluoroglycosylation: Recent Progress and Future Prospects." Pharmaceuticals 14.11 (2021).
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