Unberath P, Knell C, Prokosch HU, Christoph J (2019)
Publication Type: Book chapter / Article in edited volumes
Publication year: 2019
Publisher: IOS Press
Edited Volumes: ICT for Health Science Research
Series: Studies in Health Technology and Informatics
Book Volume: 258
Pages Range: 46-50
DOI: 10.3233/978-1-61499-959-1-46
BACKGROUND: The cBioPortal is a prevalent open-source translational research platform, allowing private instances and extensions. OBJECTIVE: Our aim was to build up an own instance of cBioPortal, identify missing functionality by interviewing researchers, and implementing these extensions. METHODS: We examined the code base of the cBioPortal and conducted a requirements analysis with researchers. Then an own extension was implemented and a usability evaluation was performed. RESULTS: We developed a new tab in the results view of cBioPortal adding the option to analyze the correlation of gene expression and mutation patterns. CONCLUSION: While extending the cBioPortal is possible, there are still some challenges to overcome. A plug-in concept and a more detailed documentation would greatly facilitate the development of own extensions.
APA:
Unberath, P., Knell, C., Prokosch, H.-U., & Christoph, J. (2019). Developing New Analysis Functions for a Translational Research Platform: Extending the cBioPortal for Cancer Genomics. In Amnon Shabo, Inge Madsen, Hans-Ulrich Prokosch, Kristiina Häyrinen, Klaus-Hendrik Wolf, Fernando Martin-Sanchez, Matthias Löbe, Thomas M. Deserno (Eds.), ICT for Health Science Research. (pp. 46-50). IOS Press.
MLA:
Unberath, Philipp, et al. "Developing New Analysis Functions for a Translational Research Platform: Extending the cBioPortal for Cancer Genomics." ICT for Health Science Research. Ed. Amnon Shabo, Inge Madsen, Hans-Ulrich Prokosch, Kristiina Häyrinen, Klaus-Hendrik Wolf, Fernando Martin-Sanchez, Matthias Löbe, Thomas M. Deserno, IOS Press, 2019. 46-50.
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