Tollens F, Baltzer PAT, Dietzel M, Schnitzer ML, Schwarze V, Kunz WG, Rink J, Ruebenthaler J, Froelich MF, Schoenberg SO, Kaiser CG (2022)
Publication Type: Journal article
Publication year: 2022
DOI: 10.1007/s00330-022-08777-5
Objectives Abbreviated breast MRI (AB-MRI) was introduced to reduce both examination and image reading times and to improve cost-effectiveness of breast cancer screening. The aim of this model-based economic study was to analyze the cost-effectiveness of full protocol breast MRI (FB-MRI) vs. AB-MRI in screening women with dense breast tissue for breast cancer. Methods Decision analysis and a Markov model were designed to model the cumulative costs and effects of biennial screening in terms of quality-adjusted life years (QALYs) from a US healthcare system perspective. Model input parameters for a cohort of women with dense breast tissue were adopted from recent literature. The impact of varying AB-MRI costs per examination as well as specificity on the resulting cost-effectiveness was modeled within deterministic sensitivity analyses. Results At an assumed cost per examination of $ 263 for AB-MRI (84% of the cost of a FB-MRI examination), the discounted cumulative costs of both MR-based strategies accounted comparably. Reducing the costs of AB-MRI below $ 259 (82% of the cost of a FB-MRI examination, respectively), the incremental cost-effectiveness ratio of FB-MRI exceeded the willingness to pay threshold and the AB-MRI-strategy should be considered preferable in terms of cost-effectiveness. Conclusions Our preliminary findings indicate that AB-MRI may be considered cost-effective compared to FB-MRI for screening women with dense breast tissue for breast cancer, as long as the costs per examination do not exceed 82% of the cost of a FB-MRI examination.
APA:
Tollens, F., Baltzer, P.A.T., Dietzel, M., Schnitzer, M.L., Schwarze, V., Kunz, W.G.,... Kaiser, C.G. (2022). Economic potential of abbreviated breast MRI for screening women with dense breast tissue for breast cancer. European Radiology. https://doi.org/10.1007/s00330-022-08777-5
MLA:
Tollens, Fabian, et al. "Economic potential of abbreviated breast MRI for screening women with dense breast tissue for breast cancer." European Radiology (2022).
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