Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study
Seyger MM, Augustin M, Sticherling M, Bachhuber T, Fang J, Hetherington J, Lucas J, Meakin S, Richardson C, Paller AS (2022)
Publication Type: Journal article
Publication year: 2022
Journal
Book Volume: 102
Article Number: adv00660
Abstract
This study is a retrospective analysis using data col-lected from the Adelphi Paediatric Psoriasis Disease-Specific Programme cross-sectional survey. Despite being treated for their psoriasis, a substantial proportion of paediatric patients presented with moderate (18.3%) or severe (1.3%) disease at sampling; 42.9% and 92.0% had a body surface area (BSA) of >10%, and 38.8% and 100.0% had a Psoriasis Area Severity Index (PASI) score >10, respectively. Overall, 69.9% of patients had only ever been treated with a topical therapy for their psoriasis. For patients with moderate or severe disease at sampling, 16.3% and 14.4% were currently receiving conventional systemics or biologic therapy, respectively. There is a clinical unmet need in this paediatric population; a considerable percen-tage of patients still experienced moderate or severe disease and persistent psoriasis symptoms, with nu-merous body areas affected. A significant proportion of patients were undertreated, which may explain the high burden of disease observed.
Authors with CRIS profile
Involved external institutions
Radboud University Nijmegen Medical Centre / Radboudumc of voluit Radboud Universitair Medisch Centrum (UMC)
Netherlands (NL)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Novartis AG
Switzerland (CH)
Adelphi Real World
United Kingdom (GB)
Northwestern University
United States (USA) (US)
Netherlands (NL)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Novartis AG
Switzerland (CH)
Adelphi Real World
United Kingdom (GB)
Northwestern University
United States (USA) (US)
How to cite
APA:
Seyger, M.M., Augustin, M., Sticherling, M., Bachhuber, T., Fang, J., Hetherington, J.,... Paller, A.S. (2022). Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study. Acta Dermato-Venereologica, 102. https://doi.org/10.2340/actadv.v101.981
MLA:
Seyger, Marieke M.B., et al. "Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study." Acta Dermato-Venereologica 102 (2022).
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