Che Y, Zschoche S, Obst F, Appelhans D, Voit B (2019)
Publication Type: Journal article
Publication year: 2019
Book Volume: 57
Pages Range: 2590-2601
Journal Issue: 24
DOI: 10.1002/pola.29539
We present novel redox-responsive hydrogels based on poly(N-isopropylacrylamide) or poly(acrylamide), consisting of a reversible disulfide crosslinking agent N,N′-bis(acryloyl)cystamine and a permanent crosslinking agent N,N′-methylenebisacrylamide for microfluidic applications. The mechanism of swelling/deswelling behavior starts with the cleavage and reformation of disulfide bonds, leading to a change of crosslinking density and crosslinking points. Raman and ultraviolet-visible spectroscopy confirm that conversion efficiency of thiol–disulfide interchange up to 99%. Rheological analysis reveals that the E modulus of hydrogel is dependent on the crosslinking density and can be repeatedly manipulated between high- and low-stiffness states over at least 5 cycles without significant decrease. Kinetic studies showed that the mechanical strength of the gels changes as the redox reaction proceeds. This process is much faster than the autonomous diffusion in the hydrogel. Moreover, cooperative diffusion coefficient (D
APA:
Che, Y., Zschoche, S., Obst, F., Appelhans, D., & Voit, B. (2019). Double-crosslinked reversible redox-responsive hydrogels based on disulfide–thiol interchange. Journal of Polymer Science Part A-Polymer Chemistry, 57(24), 2590-2601. https://doi.org/10.1002/pola.29539
MLA:
Che, Yunjiao, et al. "Double-crosslinked reversible redox-responsive hydrogels based on disulfide–thiol interchange." Journal of Polymer Science Part A-Polymer Chemistry 57.24 (2019): 2590-2601.
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