Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

Papathanasiou KE, Turhanen P, Brueckner SI, Brunner E, Demadis KD (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Scientific Reports Nature Publishing Group: Open Access Journals - Option B

Book Volume: 7

Article Number: 4743

Journal Issue: 1

DOI: 10.1038/s41598-017-04956-3

Abstract

Easy-to-prepare drug delivery systems, based on smart, silica gels have been synthesized, characterized, and studied as hosts in the controlled release of bisphosphonates. They exhibit variable release rates and final % release, depending on the nature of bisphosphonate (side-chain length, hydro-philicity/-phobicity, water-solubility), cations present, pH and temperature. These gels are robust, injectable, re-loadable and re-usable.

Involved external institutions

University of Crete / Πανεπιστήμιο Κρήτης GR Greece (GR) University of Eastern Finland FI Finland (FI) Technische Universität Dresden DE Germany (DE)

How to cite

APA:

Papathanasiou, K.E., Turhanen, P., Brueckner, S.I., Brunner, E., & Demadis, K.D. (2017). Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-04956-3

MLA:

Papathanasiou, Konstantinos E., et al. "Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs." Scientific Reports 7.1 (2017).

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