Porphyrin-Based Metal–Organic Frameworks for Biomedical Applications

Chen J, Zhu Y, Kaskel S (2021)

Publication Type: Journal article, Review article

Publication year: 2021

Journal

Angewandte Chemie International Edition Wiley

Book Volume: 60

Pages Range: 5010-5035

Journal Issue: 10

DOI: 10.1002/anie.201909880

Abstract

Porphyrins and porphyrin derivatives have been widely explored for various applications owing to their excellent photophysical and electrochemical properties. However, inherent shortcomings, such as instability and self-quenching under physiological conditions, limit their biomedical applications. In recent years, metal–organic frameworks (MOFs) have received increasing attention. The construction of porphyrin-based MOFs by introducing porphyrin molecules into MOFs or using porphyrins as organic linkers to form MOFs can combine the unique features of porphyrins and MOFs as well as overcome the limitations of porphyrins. This Review summarizes important synthesis strategies for porphyrin-based MOFs including porphyrin@MOFs, porphyrinic MOFs, and composite porphyrinic MOFs, and highlights recent achievements and progress in the development of porphyrin-based MOFs for biomedical applications in tumor therapy and biosensing. Finally, the challenges and prospects presented by this class of emerging materials for biomedical applications are discussed.

Involved external institutions

Chinese Academy of Sciences (CAS) / 中国科学院 CN China (CN) Technische Universität Dresden DE Germany (DE)

How to cite

APA:

Chen, J., Zhu, Y., & Kaskel, S. (2021). Porphyrin-Based Metal–Organic Frameworks for Biomedical Applications. Angewandte Chemie International Edition, 60(10), 5010-5035. https://doi.org/10.1002/anie.201909880

MLA:

Chen, Jiajie, Yufang Zhu, and Stefan Kaskel. "Porphyrin-Based Metal–Organic Frameworks for Biomedical Applications." Angewandte Chemie International Edition 60.10 (2021): 5010-5035.

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