Analysis of the Impact of Clinical Factors on Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Oginski N, Apel H, Richterstetter M, Lieb V, Fiebig C, Goebell P, Wullich B, Sikic D (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Urologia Internationalis Karger

DOI: 10.1159/000520705

Abstract

Introduction: Predictive factors for the treatment success of low-intensity extracorporeal shockwave therapy (Li-ESWT) for erectile dysfunction (ED) are still under debate. Methods: Li-ESWT was performed in 50 patients suffering from ED by applying 3,000 shock waves once a week over a period of 6 weeks. Treatment success was defined as an increase in the International Index of Erectile Function 5 (IIEF-5) score by >= 5 points or an Erectile Hardness Score (EHS) of >= 3 points. IIEF-5 and EHS were measured at baseline and at 3 and 6 months of follow-up. Results: Treatment success according to either the IIEF-5 score or EHS at any time of follow-up was achieved in 28 patients (56%). Twenty-five patients (50%) experienced an improvement during the first 3 months, which lasted for 6 months in 8 cases (16%). Three patients reported improved erectile function only after 6 months. When stratifying the cohort with regard to potential influencing factors, a significantly improved IIEF-5 score could be achieved in men with cardiovascular risk factors (p = 0.026) and in men with antihypertensive medication (p = 0.009). Men without cardiovascular risk factors showed no therapeutic benefit from Li-ESWT. Discussion/Conclusion: Li-ESWT is a valid but often short-lived treatment option for ED, especially in men with cardiovascular risk factors or controlled hypertension. Future studies should assess the feasibility and safety of repeated applications of Li-ESWT.

Authors with CRIS profile

Natalie Schmidt Lehrstuhl für Urologie Hendrik Apel Urologische Klinik Verena Lieb Urologische Klinik Christian Fiebig Urologische Klinik Peter Goebell Medizinische Fakultät Bernd Wullich Lehrstuhl für Urologie Danijel Sikic Medizinische Fakultät

How to cite

APA:

Oginski, N., Apel, H., Richterstetter, M., Lieb, V., Fiebig, C., Goebell, P.,... Sikic, D. (2022). Analysis of the Impact of Clinical Factors on Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction. Urologia Internationalis. https://doi.org/10.1159/000520705

MLA:

Oginski, Natalie, et al. "Analysis of the Impact of Clinical Factors on Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction." Urologia Internationalis (2022).

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