The effects of sildenafil on heart rate variability in healthy subjects
Siepmann M, Rauh R, Dill O, Agelink MW, Mück-Weymann M (2007)
Publication Type: Journal article, Original article
Publication year: 2007
Journal
Book Volume: 50
Pages Range: 598-600
Journal Issue: 5
DOI: 10.1097/FJC.0b013e318148b23d
Abstract
The effects of sildenafil on heart rate variability were investigated in 20 healthy male subjects aged 24 (21 to 32) years (median; range). Subjects orally received single 100-mg doses of sildenafil and placebo under randomized double-blind crossover conditions on 2 separate study days. Time domain measures of heart rate variability were assessed under conditions of relaxed rest, metronomic breathing (6 cycles per minute), and bicycle ergometry before administration of sildenafil and placebo as well as 60 minutes afterwards. Sildenafil did not alter heart rate nor heart rate variability to a significant extent (P > 0.05). © 2007 Lippincott Williams & Wilkins, Inc.
Authors with CRIS profile
Robert Rauh
Lehrstuhl für Physiologie (Vegetative Physiologie)
Oliver Dill
Department of Operative Dentistry and Periodontology
Involved external institutions
Germany (DE)How to cite
APA:
Siepmann, M., Rauh, R., Dill, O., Agelink, M.W., & Mück-Weymann, M. (2007). The effects of sildenafil on heart rate variability in healthy subjects. Journal of Cardiovascular Pharmacology, 50(5), 598-600. https://doi.org/10.1097/FJC.0b013e318148b23d
MLA:
Siepmann, Martin, et al. "The effects of sildenafil on heart rate variability in healthy subjects." Journal of Cardiovascular Pharmacology 50.5 (2007): 598-600.
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