The Offprint of an Abnormal Pre-Parotidectomy Electrodiagnostic Finding in a Normally Functioning Facial Nerve: Correlation with Intraoperative Findings, Histology and Postoperative Facial Nerve Function†

Katheder V, Sievert M, Müller SK, Thimsen V, Gostian AO, Balk M, Rupp R, Iro H, Mantsopoulos K (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Journal of Clinical Medicine MDPI

Book Volume: 11

Article Number: 248

Journal Issue: 1

DOI: 10.3390/jcm11010248

Abstract

The aim of this study was to search for associations between an electrodiagnostically abnormal but clinically normal facial nerve before parotidectomy and the intraoperative findings, as well as the postoperative facial nerve function. The records of all patients treated for parotid tumors between 2002 and 2021 with a preoperative House–Brackmann score of grade I but an abnormal electrophysiologic finding were studied retrospectively. A total of 285 patients were included in this study, and 222 patients had a benign lesion (77.9%), whereas 63 cases had a malignant tumor (22.1%). Electroneurographic facial nerve involvement was associated with nerve displacement in 185 cases (64.9%) and infiltration in 17 cases (6%). In 83 cases (29.1%), no tumor–nerve interface could be detected intraoperatively. An electroneurographic signal was absent despite supramaximal stimulation in 6/17 cases with nerve infiltration and in 17/268 cases without nerve infiltration (p < 0.001). The electrophysiologic involvement of a normal facial nerve is not pathognomonic for a malignancy (22%), but it presents a rather rare (~6%) sign of a “true” nerve infiltration and could also appear in tumors without any contact with the facial nerve (~29%). Of our cases, two thirds of those with an anatomic nerve preservation and facial palsy had already directly and postoperatively recovered to a major extent in the midterm.

Authors with CRIS profile

Verena Katheder Medizinische Fakultät Matti Sievert Department of Otorhinolaryngology – Head and Neck Surgery Sarina Müller-Hübner Department of Otorhinolaryngology – Head and Neck Surgery Vivian Thimsen Department of Otorhinolaryngology – Head and Neck Surgery Antoniu-Oreste Gostian Department of Otorhinolaryngology – Head and Neck Surgery Matthias Balk Department of Otorhinolaryngology – Head and Neck Surgery Robin Rupp Department of Otorhinolaryngology – Head and Neck Surgery Heinrich Iro Lehrstuhl für Hals-, Nasen- und Ohrenheilkunde Konstantinos Mantsopoulos Department of Otorhinolaryngology – Head and Neck Surgery

How to cite

APA:

Katheder, V., Sievert, M., Müller, S.K., Thimsen, V., Gostian, A.-O., Balk, M.,... Mantsopoulos, K. (2022). The Offprint of an Abnormal Pre-Parotidectomy Electrodiagnostic Finding in a Normally Functioning Facial Nerve: Correlation with Intraoperative Findings, Histology and Postoperative Facial Nerve Function†. Journal of Clinical Medicine, 11(1). https://doi.org/10.3390/jcm11010248

MLA:

Katheder, Verena, et al. "The Offprint of an Abnormal Pre-Parotidectomy Electrodiagnostic Finding in a Normally Functioning Facial Nerve: Correlation with Intraoperative Findings, Histology and Postoperative Facial Nerve Function†." Journal of Clinical Medicine 11.1 (2022).

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