Malinen AM, Bakermans J, Aalto-Setälä E, Blessing M, Bauer DL, Parilova O, Belogurov GA, Dulin D, Kapanidis AN (2022)
Publication Type: Journal article
Publication year: 2022
Book Volume: 434
Article Number: 167383
Journal Issue: 2
DOI: 10.1016/j.jmb.2021.167383
The expression of most bacterial genes commences with the binding of RNA polymerase (RNAP)–σ70 holoenzyme to the promoter DNA. This initial RNAP–promoter closed complex undergoes a series of conformational changes, including the formation of a transcription bubble on the promoter and the loading of template DNA strand into the RNAP active site; these changes lead to the catalytically active open complex (RP
APA:
Malinen, A.M., Bakermans, J., Aalto-Setälä, E., Blessing, M., Bauer, D.L., Parilova, O.,... Kapanidis, A.N. (2022). Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway. Journal of Molecular Biology, 434(2). https://dx.doi.org/10.1016/j.jmb.2021.167383
MLA:
Malinen, Anssi M., et al. "Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway." Journal of Molecular Biology 434.2 (2022).
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